Bye-Lori Good for Dyspepsia, Including Heartburn
Q Dear Dr V,
I know that Bye-Lori [containing mastic] is good for certain types of ulcers and for other gastrointestinal problems. Is it helpful for esophageal reflux? I would really appreciate an answer since this has been a problem for me for a long time and all the prescriptions I have tried in the past have not worked, or have not worked for very long.
    IK
A Dear IK,
Esophageal reflux is most commonly experienced as heartburn and may sometimes be accompanied by regurgitation of stomach contents. Heartburn is one of the most common problems seen by doctors. Esophageal reflux can be worsened by large meals, lying down, or bending over, among other things.

Esophogeal reflux is most commonly believed to be caused by an inappropriate relaxation of the lower esophogeal sphincter, which is supposed to maintain a pressure barrier between the stomach and the esophogus. However, there is evidence that multiple factors cause this pathology. Other factors include alterations of esophogeal mucosal resistance, impaired esophogeal clearance, and prolonged rates of gastric emptying (the time it takes the stomach to empty its contents into the intestine).

There is currently evidence that the eradication of the bacteria, Heliobacter pylori (H pylori),improves and/or eliminates symptoms of dyspepsia. Dyspepsia is not a disease in itself but a collection of symptoms which can include any combination of the following: heartburn; stomach discomfort and/or a sense of fullness (bloating) after eating; eructations (burping); nausea; vomiting; and/or loss of appetite. These symptoms may occur regularly or irregularly. Stress seems to increase the symptoms for many.

One study demonstrated that after treatment known to be effective for the eradication of H pyloriwas administered to H pylori-infected subjects with dyspepsia symptoms (including the symptom of esophogeal reflux), most subjects experienced significantly improved symptoms or complete resolution of their dyspepsia symptoms. These results imply that H pyloriis implicated as a causal agent in dyspepsia symptoms.

It has been clearly evidenced that mastic (found in Bye-Lori) is effective at destroying H pyloriamong other types of bacteria. So it is plausable that a gastrointestinal disturbance whose underlying cause is associated with H pylori,or other possible bacteria for which mastic is effective, may be improved by the use of Bye-Lori (containing mastic).

Mastic is exceptionally safe. So a trial of Bye-Lori may prove to be worthwhile, especially since everything else has been ineffective for you. Please note, it is important that you see your doctor for a physical exam if you have not already done so to make certain that you have no medical conditions which need attention.

Other practical things that might help to lessen heartburn:

  1. Avoid foods high in fat or carbohydrates, alcohol, peppermint, onions, coffee/tea, citrus foods, items high in acid, or anything that you know aggravates symptoms.
  2. Reduce weight if obese.
  3. Avoid large meals, especially near bedtime.
  4. Elevate head in bed rather than lying horizontally.
  5. Avoid medications which decrease sphincter tone, such as theophylline, calcium-channel blockers, and anticholinergics.
Please let me know how Bye-Lori works for your reflux, Dr V

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