Huperzine and Galantamine Together?

Q Can huperzine be taken with galantamine?

Sam, Miami

A There would probably be little if any added benefit. As far as we know, no studies have ever been done comparing the two nutritional supplements. However, because of the dual action of galantamine, both as an acetylcholinesterase inhibitor and as a nicotinic receptor modulator, galantamine remains the better choice, especially if price is not an object. A galantamine supplement may also contain choline and vitamin B5, so you would get the added benefit of having the precursor and cofactor for the production of added acetylcholine. Finally, the research on galantamine is much more solid, involving thousands and thousands of research subjects.