Durk Pearson & Sandy Shaw’s®
Life Extension NewsTM
Volume 15 No.
2 • March-April 2012
Some Natural Products Have Potent
Natural products have been investigated extensively for their antiinflammatory effects. Protection against inflammation has been reported for curcumin, orange juice, fish oils, grape skin extract and the cognition enhancer vinpocetine, to name just a few. See
the first article in this issue for information on vitamin D3, an important regulator of immune system-induced inflammation.
- Aggarwal. Targeting inflammation-induced obesity and metabolic diseases by curcumin and other nutraceuticals. Annu Rev Nutr 30:173-99 (2010).
- Ghanim et al. Orange juice neutralizes the proinflammatory effect of a high-fat high-carbohydrate meal and prevents endotoxin increase and Toll-like receptor expression. Am J Clin Nutr 91:940-9 (2010).
- Bouwens et al. Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells. Am J Clin Nutr 90:415-24 (2009).
- Hogan et al. Dietary supplementation of grape skin extract improves glycemia and inflammation in diet-induced obese mice fed a Western high fat diet. J Agric Food Chem 59:3033-41 (2011).
- Medina. Vinpocetine as a potent antiinflammatory agent. Proc Natl Acad Sci USA 107(22):9921-2 (2010).