Durk Pearson & Sandy Shaw’s^®
Life Extension News^TM
Volume 15 No. 2 • March-April 2012

Natural products have been investigated extensively for their antiinflammatory effects. Protection against inflammation has been reported for curcumin,¹ orange juice,² fish oils,³ grape skin extract⁴ and the cognition enhancer vinpocetine,⁵ to name just a few. See the first article in this issue for information on vitamin D3, an important regulator of immune sys­tem-induced inflammation.

References

1. Aggarwal. Targeting inflammation-induced obesity and metabolic diseases by curcumin and other nutraceuticals. Annu Rev Nutr 30:173-99 (2010).
2. Ghanim et al. Orange juice neutralizes the proinflammatory effect of a high-fat high-carbohydrate meal and prevents endotoxin increase and Toll-like receptor expression. Am J Clin Nutr 91:940-9 (2010).
3. Bouwens et al. Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells. Am J Clin Nutr 90:415-24 (2009).
4. Hogan et al. Dietary supplementation of grape skin extract improves glycemia and inflammation in diet-induced obese mice fed a Western high fat diet. J Agric Food Chem 59:3033-41 (2011).
5. Medina. Vinpocetine as a potent antiinflammatory agent. Proc Natl Acad Sci USA 107(22):9921-2 (2010).