Mastic Heals
From Opinion to Science

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Science is the father of knowledge, but opinion breeds ignorance.
— Hippocrates

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3. Warren and Marshall discovered _____ pylori in 1983 and correlated it with gastric diseases—for which they were awarded a Nobel Prize in 2005. Clue: A bacteria with a helix shape

5. Other research has shown mastic to be effective against the bacterium Streptococcus mutans, which is the chief culprit in periodontal disease because of its dominant role in the formation of dental ____. Clue: Sticky deposits on teeth in which bacteria proliferate.

8. As a complement to its gastrointestinal activity, ___ has been proven to possess anti-Crohn’s disease properties.

10. According to Herodotus, the chewing of mastic was beneficial to the oral cavity and the ___. Clue: An organ that is the first part of the digestive system

13. According to this double-blind clinical trial, (J Clin Exp Pharm Physiol 1984), 80% of ____ ulcer patients receiving mastic reported relief from the symptoms, compared to 50% of those receiving placebo.

15. Galen not only used it for healing stomach­aches, but also recommended it as an antidote for a ____. Clue: An injury caused by a long, slithery reptilian


1. In a 2003 study, researchers thought that mastic could both be used as a _____ in pharmaceutical and cosmetic preparations, as well as for functional foods. Clue: Substances against decay

2. It has been suggested that chewing mastic gum could be considered as a ____ nontoxic agent in the treatment of oral malodor and gum disease. Clue: Likely

3. Who was so wise to say, “Science is the father of knowledge, but opinion breeds ignorance.”? Clue: The Greek physician; the father of Western medicine

4. Several studies support the _____ activity of mastic. Clue: Reduces the activity of carcinogens

6. The 2005 Balan et al reseachers ___ that mastic possesses antitumor activity against human colorectal cancer. Clue: Came to an agreement

7. Mastic is an ______ source of biologically active compounds. Clue: Organic

9. It was the contention of Hippocrates that mastic is good for a myriad of_____. Clue: Illnesses

11. After several inconclusive but revealing mastic studies, before 2005, it was then determined that mastic’s activity should be considered as a result of ___ between numerous or even all of its components. Clue: Agents that produce a combined effect greater than the sum of their separate effects

12. Dioscorides said that mastic is “beneficial for blood coagulation, for healing chronic cough, for stomach aches; also useful for cleaning the teeth, ___the mouth when chewed and giving glow to the face when used as an ointment.” Clue: Reducing smells

14. The background of this puzzle is a copy of the 12th Century Byzantine manuscript of the Hippocratic ____. Clue: Anyone who is smart enough to read our magazine will find this answer a breeze

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