Top Scientists Agree
Metformin is an antiaging drug

by Dr. Joyce Block

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ACROSS

1. Among Dean and Dilman’s list of benefits shared by Phenformin and Metformin is the ____ in the development of atherosclerosis. Clue: The word cookbooks use to describe cooking a sauce down to its tasty elements

7. Researchers also show that Metformin assists us in reduced low-density ____ and cholesterol levels without a lower intake of calories. Clue: LDL, the “bad” actor in the cholesterol community

9. With age, there is a progressive loss of insulin sensitivity. Does this suggest that we are all diabetics or prediabetics? Yes or no? Clue: If you understand diabetes basics you know this one

10. Because Metformin treatment has been associated with reduced risk of ___ and cardiovascular disease, the possibility of a beneficial role of Metformin for other age-related diseases is suggested. Clue: The Big “C,” a reason to pay attention to the information here

12. Dr. Dean wrote, “I strongly encourage all of my ____ over the age of 40 to take 500 mg of Metformin two or three times per day.” Clue: Those who enlist the help of a doctor

13. In their book, The Neuroendocrine Theory of Aging and Degenerative Disease, (Dilman and ____, 1992), list the benefits of Phenformin, which they believe are shared by Metformin. Clue: One of Life ­Enhancement’s well-known formulators and scientists, Dr. Ward ____

14. The researchers show that treatment with Metformin mimics some of the benefits of calorie restriction, including improved ___ performance. Clue: The kind of performance that an otherwise healthy who person who “lives on the couch,” tends not to seek out

15. “One of the most universal changes with age is a progressive loss of glucose tolerance,” writes Life Enhancement’s Dr. Ward Dean, an early ____ of metformin. Clue: Advocate

DOWN

1. Type-2 diabetes is a metabolic disorder that is characterized by high blood glucose in the context of insulin ___ and relative insulin deficiency. Clue: Opposition

2. If the same ____ were used for older people as are used for younger people, nearly every senior citizen would be diagnosed as diabetic. Clue: standard

3. ____ is an oral antidiabetic drug used for the treatment of type-2 diabetes. Clue: Mnemonic device; we met at the forum for a minute

4. Another benefit listed by Dilman and Dean is that Metformin and Phenformin can benefit us by improving cellular ____. Clue: An organism’s ability to resist a toxin or infection

5. Who is the medical coauthor along with the Russian scientist shown on the front cover of his book? Clue: One name, three words, no spaces in between.

6. In ____ and Shaw’s August 2013 article, “For Those Using Metformin, Good News,” Metformin when combined with oligofructose has “the potential to improve metabolic outcomes associated with obesity.” Clue: One of our formulators who also worked on all of the manned aerospace programs from Project Gemini to the Space Shuttle and won numerous awards

8. According to Dr. Dean, “Diabetes is believed by many gerontologists to be an example of accelerated or ___ aging. Clue: Before its time

11. Based on a new Nature Communications male mice study, the authors strongly suggest that Metformin could lead to improved health-span and ___ in humans too. Clue: The beginning, middle and end of life as we know it

Crossword Contest
Win a $10 credit toward a $50 purchase by:
Submitting a correctly answered puzzle each
month by the 15th of the next month.

Send to:
Attn: Dr. Joyce Block
Life Enhancement Contest
2555 Business Parkway
Minden, Nevada 89423

P.S. Last month's contest was not listed, however, all of September's puzzles will be accepted until October 15, 2013

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