Biomedical Updates


Curcumin/Boswellia Shows Promise for Kidney Health

C hronic kidney disease (CKD) is characterized by a continuous reduction in kidney function, increased inflammation, and reduced antioxidant capacity. In a new study, the objective of the researchers was to assess the effects of Curcuma longa (Turmeric) and Boswellia serrata on systemic inflammation and antioxidant status in non-dialysis CKD patients.1

Sixteen patients with CKD (56.0±16.0 years) were randomly chosen to receive the two supplements or placebo. Measured at 8 weeks were plasma levels of interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), glutathione peroxidase (GPx), and serum C-reactive protein (CRP).

At the beginning of the study, baseline measurements demonstrated elevated inflammation and low antioxidant levels. At the study’s conclusion, those who received curcumin and Boswellia serrata experienced a reduction in interleukin-6 in comparison with pretreatment values, indicating decreased inflammation, while IL-6 values rose among those who received a placebo. Although tumor-necrosis factor-alpha was not reduced in the current study, researchers observed that the ACE inhibiting drugs used by the majority of the patients, which are known to lower tumor-necrosis factor-alpha, could have influenced the results.

Reference

  1. Moreillon JJ, Bowden RG, Deike E, Griggs J, Wilson R, Shelmadine B, Cooke M, Beaujean A. The use of an anti-inflammatory supplement in patients with chronic kidney disease. J Complement Integr Med. 2013 Jul 1;10.

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