Exclusive Interview with SmartzTM Designers
Durk Pearson & Sandy Shaw®
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Introducing the World's First Mental Fitness® Soft Drink

With the creation of Smartz - the world's first Mental Fitness soft drink - we stand, figuratively, at the grand opening of the next millennium. The development stage has lasted a long time, but our patience has been worth it. Designed by life extension scientists Durk Pearson & Sandy Shaw, Smartz is a psychobiochemical achievement and not a loosely-constructed herbal concoction. Its creation is derived from an intimate knowledge of the body's metabolic pathways. Its nutrient composition is scientifically designed to economically produce supplemental amounts of natural and necessary neurotransmitters and neuromodulators in your brain. What's more, it tastes great!

The concept of food represented by Smartz - Durk & Sandy call it a Designer Food® - is revolutionary. As Sandy says, "Before this century, people had little more to go on other than their feelings. If the food made them feel energized or better in some way, that's all they had to go on." As a scientifically designed food, Smartz is the capstone of the progress we've made. By opening the bridge that crosses the blood-brain barrier and delivering the nutrients your brain needs to function properly, we can - despite our age - enhance our mental fitness. We do not have to wither mentally but can grow wiser as we move more ably into the information age. There we will need every connection, every mental bridge, and every emotional intensifier that life warrants and deserves.

Previous to Smartz technology, there was no sure-fire way to obtain the benefits of mental fitness. Congratulations to everyone involved in this historic undertaking. Cut the tape. Open the doors to the new Century. The introduction of Smartz is the kick-off for the information millennium. 


WILL: In order to understand the value of your new Mental Fitness soft drink Smartz, where do we begin?

DURK: Let's start at the start.

Every thought, every memory, every emotion, even the will to move a muscle is caused by the release of neurotransmitters in your brain.


The introduction of
Smartz is the kick-off
for the information
millennium.

Neurotransmitters are not drugs. They are natural substances made from nutrients by neurons in your brain. Neurotransmitters transmit information from one neuron to another, which is why they are called neurotransmitters.

Over the years, we have developed a family of products for our own personal use based upon a simple idea: To provide our brains with nutrient raw materials they can use to support their supplies of the neurotransmitters noradrenaline (also called norepinephrine, our brain's version of adrenaline), dopamine, and acetylcholine.

Smartz, our latest and most technologically advanced formulation in this series, is a dietary supplement for your brain disguised as a delicious carbonated beverage.

Using metabolic pathway charts that showed us (like a highway map) different routes that nutrients can take when used by our brains and bodies, we designed appropriate systems of nutrients to provide Designer Food dietary supplements for our brains. These are literally brain foods.

The conventional soft drink, which is simply sugar, caffeine and carbonated water, is as technologically obsolete as a mule-drawn buckboard or a sleigh being pulled by reindeer. Pepsi-Cola and Coca-Cola don't realize this yet; but 20 years from now, I doubt if such drinks are going to even be on the market anymore. They simply don't deliver what people want.

SANDY: Well, except for the flavor. You know people like the cola taste.

DURK: But it doesn't do anything for you . . .

SANDY: That's just like, "The ones that mother gives you . . .

DURK & SANDY (in unison): . . . don't do anything at all."

(Laughter)

DURK: That's from Jefferson Airplane's "White Rabbit."

SANDY: The caffeine in colas is a very effective stimulant. And it's safe enough that almost anybody can use reasonable amounts of it. That's why you find it in so many drinks. However, it's limited in what it can do.

DURK: It's a lot better when you have other factors - nutritional factors - such as the amino acid phenylalanine and other nutritional cofactors needed to turn the phenylalanine into beta phenylethylamine and noradrenaline and dopamine; neuromodulators and neurotransmitters critical for proper brain functioning. Smartz contains these nutritional factors. Also, when you have an abundance of these factors, caffeine works a heck of a lot better. You can get a lot more out of caffeine if you have those other nutrients with it. While conventional soft drinks are the ultimate in empty calories, Smartz is chock-full of nutrition for your brain.


Yes, our Smartz formulation
fulfills a dream that we've
had for a long time

Years ago, we read a paper about carbon dioxide increasing blood flow to the brain by causing vasodilation in the brain, and it also increased permeability of the blood-brain barrier.

Consequently, nutritional factors that were in circulation in the blood stream could get across the blood-brain barrier and into the brain more easily.

SANDY: This was a real eye opener because it showed that the carbonation in carbonated drinks didn't have to be just something that tasted good or made your tongue feel happy by fizzing on it. Carbonation actually has physiological effects.

DURK: Instead of people drinking carbonated water, the people in the study breathed in carbon dioxide (CO2). There were dramatic changes resulting in both increased blood flow to the brain and blood-brain barrier permeability. So we thought, "Let's try carbonating a combination of our phenylalanine and choline drink mix formulations." Well, if you simply try adding them to carbonated water, which is the first thing we did, the fruit acids caused most of the CO2 to leave very rapidly; and you have very little of the CO2 left in the water.


While conventional soft
drinks are the ultimate in
empty calories, Smartz is
chock-full of nutrition for
your brain.

SANDY: The CO2 foamed right out. It was incredible. And messy.

DURK: So we tried using a seltzer bottle by mixing our powder mixtures with water, refrigerating it inside the seltzer bottle - letting it get good and cold - and then charging it up with a cartridge of CO2 after it was cold; the solubility of CO2 is much higher in cold water than in warm water. When we squirted it out of the seltzer bottle into a glass - boy, was that ever good!

SANDY: Yes, it was great! Although it was inconvenient.

DURK: And expensive too . . . but the effects were wonderful. Not only did the flavor spring up into our nasal passages more readily, the carbon dioxide did too. CO2 is absorbed into the blood stream feeding your palette, your mouth, your nose and your sinuses, all of which carry the CO2 directly to your brain. CO2 opens up your blood vessels, resulting in increased blood flow. And it also opens up the blood-brain barrier so more of the nutrients that are carried by the blood can get into your brain. And the cognitive effects come on substantially faster and stronger. It was exactly what we had hoped for.

However, not only was the process costly and inconvenient, the valves of seltzer bottles are not designed to handle anything other than carbonated water. The ingredients, and especially the fructose, caused a sticky mess, preventing the valve from sealing properly and the seltzer bottle from holding pressure, unless it was carefully washed out after each use.

SANDY: So we never did make a carbonated version of these particular formulations available commercially. And we didn't use the apparatus very long ourselves either because it was just too inconvenient.

DURK: It was a lot of work.

WILL: But now with the arrival of Smartz, the world's first mental fitness soft drink, we have convenience and much, much more.

SANDY: Yes, our Smartz formulation fulfills a dream that we've had for a long time. It's wonderful because a drink like this will give countless people an opportunity to feed their heads and to experience the effects of our phenylalanine and choline drink mixes together. And with the carbonation, you can actually get more sensation than just simply mixing the two together.


In fact, if you remain mentally
active and use your mind a lot,
you're actually protecting
neurons, especially cholinergic
neurons, from destruction.

DURK: And it makes conventional soft drinks look like "the ones that mother gives you that don't do anything at all," to quote Grace Slick from "White Rabbit."

WILL: Caffeine is conventional to soft drinks. But you've said that it's not enough. Why?

DURK: Caffeine is the world's most popular recreational and work ethic drug, and for a good reason. It actually enables you to work harder and more accurately if you take the right amount at the right time. However, anybody who uses caffeine knows that there are certain problems with it. The first cup of coffee really gets you up in the morning, makes you bright-eyed and bushy-tailed, gets you working hard, really makes you alert, and improves your performance. But the second cup doesn't do as well as the first and the third cup doesn't do as well as the second. By the end of the day, you may have drunk a whole pot of coffee and may feel all spaced out, nervous and irritable.

SANDY: It's not improving your performance anymore. Instead of improved performance, you're just getting the unwanted side effects.


Smartz takes normal
nutrients that appear in a
normal, healthy diet and
helps get them across the
blood-brain barrier and into
the brain.

DURK: To understand what's going on here, you need to understand that caffeine works by two known mechanisms. One of the things that it does is antagonize the adenosine receptors. Adenosine is an inhibitory neurotransmitter in the brain, high levels of which make you sleepy. And inhibiting an inhibitor tends to wake you up, which is one of the reasons why caffeine acts as a stimulant. It takes a rather large amount of caffeine to do that. I'm not sure that this mechanism plays much of a role at the 40 mg amount in a typical caffeine-containing soft drink.

The other caffeine mechanism causes you to release noradrenaline, the brain's version of adrenaline, and it makes you more sensitive to the effects of a given amount of noradrenaline. When noradrenaline activates a receptor at the outer surface of a cell, the message is transmitted inside the cell by a second messenger, cyclic AMP. The cyclic AMP is destroyed by an enzyme, cAMP phosphodiesterase, thereby terminating the message originally sent by the noradrenaline. Caffeine inhibits cAMP phosphodiesterase, thereby prolonging and intensifying the message. Unfortunately, caffeine doesn't help you to make any more noradrenaline. This is why some doctors advise their patients not to use caffeine because it is said to deplete noradrenaline. What it's really doing is making them use up their noradrenaline faster.


Smartz really is a work-
ethic formulation that
enables you to work harder
and makes you feel better
about working harder

Of course, there are little or no nutrients in a typical soft drink, other than sugar. As a result, you don't have anything there to replace the lost supplies. We designed some drink mix formulations to provide phenylalanine which (with the help of the cofactors Vitamin B6, Vitamin C, folic acid and copper) is converted into noradrenaline and dopamine. It's also converted into beta phenylethylamine, which is a neuromodulator. Perhaps people's experiences with beta phenylethylamine are best described by what happens when you eat chocolate. Chocolate is one of the richest food sources of beta phenylethylamine. It seems to make emotions more intense. You might say it's an intensifier for emotions involving noradrenaline and dopamine.

WILL: That's interesting. With chocolate being associated with, say, Valentine's Day, would it actually amplify the emotions of love as well?

DURK: I would certainly think so. I have taken beta phenylethylamine separately, though it doesn't cross the blood-brain barrier very well, but some does get across. It does seem to be an emotional intensifier. But if you take our phenylalanine formulations, you'll get all those nutrients into your brain. Then your brain will have the precursors and cofactors to make physiologically appropriate amounts of beta phenylethylamine, noradrenaline and dopamine.

SANDY: And release these when it considers it the right time to do so. The nutrient precursor/cofactor technology of our formulations leaves all of the natural physiological regulatory systems in place for determining how much is released and when it's released. Thus, our formulations don't bypass any of your body's built-in regulations.

Whereas when you take a final substance, such as an intracerebral injection of noradrenaline or dopamine, the control steps that determine when things are released are bypassed. This is something you have to be very careful about. It's the difference between taking growth hormone directly as an injection and taking a growth hormone releaser comprised of nutrients. When you take growth hormone directly, all the regulatory mechanisms that determine when it's released and how much is released are skipped.

DURK: Whereas if you take arginine, choline and Vitamin B5, your body uses them in a normal manner to facilitate the natural release of growth hormone. And you're not going to get non-physiological levels of growth hormone or non-physiological patterns of its release, both of which can cause problems.

That's one of the big differences between drug stimulants and this type of formulation. With the dangerous drug-type stimulants, you're hitting yourself over the head with a sledgehammer. Cocaine and methamphetamine block dopamine reuptake and you get very non-physiological results. It's not too surprising people end up in trouble taking those.

WILL: How much of an age-related decline is there in the ability to produce noradrenaline?


Smartz is a dietary
supplement and a soft drink.
It's put together like a soft
drink, and is fun and
refreshing like a soft drink,
but it really is a dietary
supplement. For that
reason, you should read the
label before you use the
product.

DURK: Aging results in a substantial decrease in the ability to produce both noradrenaline and dopamine, and the problem is even worse with acetylcholine. Aging also reduces receptor sensitivity and the ability of the transmitter neuron to reuptake and reuse noradrenaline, dopamine, or the acetylcholine precursor choline. Also, aging reduces the ability to uptake antioxidant nutrients. This is particularly a problem because noradrenaline and dopamine can both act as antioxidants in the presence of adequate amounts of other antioxidants, but if antioxidants are inadequate, noradrenaline and dopamine can behave as pro-oxidants.

The drop-off with age is even more dramatic with respect to two other components, choline and Vitamin B5, of the Smartz formulation. The ability of a person's brain to uptake choline from their blood stream drops very dramatically with age. When you're in your 70s, you may have only 15% of your brain's choline uptake ability compared to what you had as a young adult. One of the interesting things about the cholinergic nerves is that they require cholinergic stimulation on a continuing basis or they tend to die off. This may be part of the problem contributing to senile dementia.

SANDY: This is the "use it or lose it phenomenon." In fact, if you remain mentally active and use your mind a lot, you're actually protecting neurons, especially cholinergic neurons, from destruction.

WILL: There's a limit on the amount that you can or should take of anything. What's the right amount of noradrenaline precursors and cofactors?


Smartz is a drink that
has been designed to
provide nutrients for
your brain.
Literally,
brain food.

DURK: We produce formulations - Smartz included - that take normal nutrients that appear in a normal, healthy diet and help get them across the blood-brain barrier and into the brain. And then the brain's biochemistry can make appropriate amounts of neurotransmitters and release them at appropriate times. For example, the reward juice dopamine is made and then gets released under normally rewarding conditions, situations such as accomplishments, sex, and so forth.

SANDY: With dangerous drug-type stimulants such as cocaine, it's really perverse to be getting a positive reward when you haven't done anything that's life-promoting and that would normally result in your feeling a sense of accomplishment or reward.

DURK: Smartz gives you more energy so you can accomplish more. It then enables you to experience more reward out of that given accomplishment. So, all in all, Smartz really is a work-ethic formulation that enables you to work harder and makes you feel better about working harder. It provides you with the neurological substrates you need. As to recommended use, we suggest three to four servings per day. We suggest taking a Smartz as soon as you get up in the morning. Then take another serving about an hour or so before lunch, and then a third serving in mid-afternoon. And if you have a whole lot of work to do, you might want to take a fourth serving in late-afternoon.

WILL: So 7:00 am, 11:00 am and, say, 3:00 pm for three servings?

DURK: Yes, that's about the right times.

SANDY: Smartz is a dietary supplement and a soft drink. It's put together like a soft drink, and is fun and refreshing like a soft drink, but it really is a dietary supplement. For that reason, you should read the label before you use the product.

DURK: And remember that Smartz isn't something like "the ones that mother gives you that don't do anything at all." This definitely does something to you and you need to understand that and read the label. For example, if you have PKU or if you are taking anticholinergic prescription drugs, you wouldn't want to use it. Be sure to read the label because this formulation will have a physiological effect on you.

WILL: One of the interesting things about having Smartz is the convenience - the absolute convenience - of it. And I'm constantly finding new uses for it . . . especially when I want to amplify being more alive and more aware of something I'm doing. It's fun and easy to be able to drink a Smartz wherever I go. Just pop the top and there you are. [Pop.] Ready to drink and scintillatingly delicious.

DURK: Yes. This is something that we've found, too. We have a whole bunch of them in our refrigerator and we drink them frequently. One of the advantages is that the reward is convenient and immediate. You pop the top and start drinking it and it starts working faster than a mixture of one of the phenylalanine drinks with the choline drink.

Drinking it cold right out of the can without pouring it into a glass or over ice maximizes the delivery of CO2 to your blood-brain barrier and other brain vasculature.

SANDY: It's so handy, we take it with us when we're going out to the countryside to see our cattle or springs. It's just a fantastic snack or pick-me-up anytime we feel like drinking it.

DURK: Smartz is also useful for someone who's getting a little bit plump as they get older. Drinking Smartz an hour before a meal will really help satisfy your appetite with a lot fewer calories. Smartz uses real fruit sugar, fructose, as a sweetener, instead of the "high fructose corn syrup" you find in regular soft drinks. "High fructose corn syrup" can contain as little as 42% fructose to usually no more than 55%, the rest being glucose. At around half glucose, regular soft drinks release a lot of insulin which brings your blood sugar back down over the next couple of hours. That may result in excess residual insulin, lower blood sugar than normal and increased hunger. In fact, with a regular can of soda pop an hour or two before a meal, you may be hungrier at the meal than if you had nothing. With Smartz an hour beforehand, you do not get this big insulin kick, which subsequently depletes your blood sugar and makes you hungry an hour or two later. The fructose in a can of Smartz releases less insulin than 1 oz of skim milk.

WILL: I've really noticed the appetite satisfaction. Other people have been reporting this too.

SANDY: We've always thought that there was a sort of philosophical aspect to the drink: If all of us could become smarter, we could create a better world. It would be more likely that there would be peace in the world. And it would be more likely that politicians wouldn't get away with all of the outrageous things they keep pulling off - the lies and deception and so forth. Because people would be smart enough to think more critically and think for themselves.


One of the interesting things
about having Smartz is the
convenience - the absolute
convenience - of it.

It seems like an impossible idea that people could become smarter, especially with the inferior educational system that the government has imposed upon us. But in fact, it is possible for people to get smarter and become more assertive by using the right nutrients; and this is something that we think is going to eventually become commonplace. And when it does, it's going to change the world.

WILL: Can Smartz increase your IQ?

SANDY: Smartz is not likely to change the results of an IQ test - remember that intelligence is made up of a large number of different abilities - but it can make you smarter in terms of accomplishments. The results are likely to be individualized. And that's something that you'll notice yourself, just by comparing the way you're performing your normal everyday activities when drinking Smartz. I sure notice a difference. It makes a fantastic difference, first of all in terms of motivation. I'm a lot more likely to get out there and get something done when I use Smartz.


Smartz gives you more
energy so you can
accomplish more. It then
enables you to experience
more reward out of that
given accomplishment.

WILL: The ingredients in Smartz, the amounts of phenylalanine, the amounts of choline and Vitamin B5 and so on - is it possible to get these levels in a typical diet?

DURK: Well, the phenylalanine, yes; however, you're going to be getting it as part of protein, so relatively little of that will get to your brain because of competition with other similar type (large neutral) amino acids.

WILL: Explain a little bit more how that works.

DURK: A lot of things get into your brain across the blood-brain barrier by a process called active transport.

SANDY: In other words, nutrients don't necessarily just diffuse across. There are transporter molecules at the blood-brain barrier that actually pick up and carry particular nutrients into the brain.

WILL: Kind of like ferries or buses . . .


It's fun and easy to be able to
drink a Smartz wherever I go.
Just pop the top and there
you are. Ready to drink and
scintillatingly delicious.

DURK: Exactly. Imagine a scene in a Japanese subway station where it's rush hour and people are pouring into the subway cars. Then you have more people packing and pushing them in. But eventually the car gets full and that's it. Now let's suppose that you have labels on all these different people: phenylalanine, tyrosine, tryptophan, valine, etc. If you have a whole bunch of different people getting into the car with a whole bunch of these different labels, the number of phenylalanines that can get into the car is limited by the presence of all these other competitors. When you drink Smartz, you get something that you don't get in a hamburger. If you eat a big McDonald's hamburger, you can get as much phenylalanine as you get in a Smartz. However, in addition to a lot of calories and fat, you're going to get a lot of other amino acids in that hamburger which are going to compete with phenylalanine passage across the blood-brain barrier. So you're not going to be very efficient in getting much of that phenylalanine into your brain with the hamburger. Not only that, the hamburger is going to release a great deal of insulin. And that insulin is going to take a lot of those amino acids and drive them out of your blood stream into other tissues. And that includes phenylalanine. In other words, there will soon be less available phenylalanine in your blood stream than if you took the same amount of phenylalanine alone. And because of the competition, there will be even less phenylalanine getting into your brain.

WILL: So instead of waking up from that hamburger and having an increased awareness, you're likely to have a decreased awareness.

DURK: Exactly. What will happen is you're likely to get sleepy because the insulin doesn't move tryptophan into your other tissues as readily as it moves the phenylalanine. And so, as a result, more tryptophan gets into your brain after a hamburger and it is converted there to serotonin and it makes you drowsy.

SANDY: This is compounded by the carbohydrates in the bun and the sugar typically added to the sauce.

WILL: There are a lot of other ingredients in Smartz that are not present in adequate amounts in food.

DURK: Oh sure. You won't find more than a trace of taurine in food unless you're eating liver and there's no way you could eat enough liver to get the 400 mg of taurine in Smartz. The reason taurine is included is to help modulate the possible stimulating effects of the 40 mg caffeine, the same amount you find in a typical cola drink. To remind you again, when you drink Smartz, you're also consuming phenylalanine and the nutrient cofactors for making noradrenaline and dopamine and beta phenylethylamine. Taurine is a neuromodulator that helps prevent excessive sensitivity to noradrenaline, which can be more pronounced because of the presence of caffeine. You can get energy, but without the jitters or the edginess associated with caffeine.

SANDY: Taurine, also an important antioxidant in the brain, is particularly rich in foods that are highly vascularized like red meat. But because a lot of people are reducing red meat consumption, the amount of taurine people are getting in their diet is likely to be dropping.


Drinking Smartz an hour
before a meal will really
help satisfy your appetite
with a lot fewer calories

DURK: In fact, if you ate nothing but red meat, there's no way you could get 400 mg of taurine per day, let alone 400 mg per serving. Similarly, we've got a couple of RDAs of Vitamin C in there, and an RDA of Vitamin E. This is, again, something that you're not going to get out of most ordinary dietary foods. As for the choline, I don't know how much fish you have to eat to get 300 mg but it would be an awful lot. Similarly, you could eat the healthiest foods in the world - stuffing yourself with 4,000 calories a day - and you would not get the 10 mg of Vitamin B6 contained in one can of Smartz. Something like 80% of the U.S. population is deficient in Vitamin B6, even by the FDA's meager RDA standards. And we think the RDAs for Vitamin B6 are much too low.

SANDY: More and more scientists now agree with this because of the positive effect higher levels of Vitamin B6 have on lowering the blood levels of homocysteine, which is strongly implicated in cardiovascular disease.

DURK: And you would have to eat an awful lot of royal jelly to get 160 mg of Vitamin B5.

WILL: What are the consequences of not getting enough of the right nutrients?

DURK: The essential nutrient levels are high enough in a typical diet to prevent you from dying from noradrenaline deficiency. But these levels are not the optimal amounts in terms of getting the sort of energy you need for a 60-hour mentally intense work week.

SANDY: Knowing the biochemistry that's involved is a revolutionary way of looking at foods. Before this century people had little more to go on other than their feelings. If the food - like, say, coffee beans - made them feel energized or better in some way, that's all they had to go on.


The fructose in a can of Smartz
releases less insulin than
one ounce of skim milk.

DURK: There was some traditional knowledge such as brown rice prevented pellagra, whereas white rice encouraged it. Lime juice prevented scurvy on long ocean voyages.

SANDY: But people didn't have much of an idea of what was going on there in terms of the science of nutrition. Whereas now, we're really getting down to the details of what it is that's in the food that's producing these effects that people want, the nutritional effects.

DURK: And that's why we've designed our foods to have specific biochemical functional effects. And it's based upon detailed scientific knowledge of the intermediary metabolism of the nutrients and what your body does with what you eat. If you know the chemical details, the biochemical details of how one thing is converted into another, you can take specific nutrients that you need in specific combinations and amounts to enable that process.

SANDY: Exactly. And Smartz is a drink that has been designed to provide nutrients for your brain.

DURK: Literally, brain food.

WILL: Is there any scientific literature demonstrating the effectiveness of taking phenylalanine plus cofactors, in producing an abundance of neurotransmitters and neuromodulators in the brain?

DURK: A few experiments have been done to determine the anti-fatiguing effects of phenylalanine. In a Japanese study, people were given very difficult mental tasks to perform. While phenylalanine supplements didn't provide much help if the person only had to work for a couple of hours, phenylalanine really did improve their ability to perform when the work went on for longer periods. A person was able to generate enough noradrenaline and dopamine over a period of a couple of hours for these difficult mental tasks, but beyond a couple of hours, supplements were needed to improve performance. When the subjects didn't get extra phenylalanine, they pooped out after a few hours and didn't have enough to do an optimum job beyond that.

SANDY: Imaging studies can follow the areas in the brain where the greatest amount of metabolism is taking place, where the most energy is being used, especially for particular kinds of mental tasks.

DURK: One of the things we'd like to do, if Smartz is able to allow it in their promotional budget, is to have some functional MRI studies done on people drinking Smartz and solving difficult problems. This hasn't been done yet.

WILL: What kind of studies have been done with choline?

DURK: Choline can be used to make acetylcholine, which is a neurotransmitter in your brain that has a lot of different uses. It's involved in verbal behavior, memory, and focusing attention. Experiments have been done showing that on difficult mental tasks involving verbal behavior, a choline supplement can improve performance particularly for memorization of a list of highly abstract words like justice, quantum, truth, honor. This is a much more difficult list of words to memorize because there are no images inherently associated with the words. And nowadays of course, people aren't just dealing with high-imagery words like horses, dogs, and cats but with Y2K bugs and quantum mechanics.

SANDY: Exactly. The vocabulary that really distinguishes somebody who is educated is made up of a lot of high-tech words that frequently don't have any images associated with them.

WILL: With the way that knowledge is evolving, I would think that choline has a great continued future as a supplement.

DURK: For anybody who makes a living with their brain, Smartz is going to be especially useful. If you're going to go out and dig a ditch with a shovel, Smartz is good because it will help get you out there with the darn shovel digging the dog-goned ditch, which may not in itself be a very rewarding task, but it's something you've got to do if you're a rancher and you want to get the water down to the pasture.

SANDY: If you're doing this sort of task and you enjoy daydreaming at the same time or parallel thinking while you're doing this sort of brainless activity, then Smartz is great for that too.

DURK: I've found that Smartz is very useful when I have to dig out a spring that's gotten filled up with windblown dust and sand. I'll tell you, Smartz makes it a lot easier to go out there, do the job, get it done, and feel really good about doing it.

SANDY: Smartz is also a fun drink, and not good just for putting your nose to the grindstone and doing a lot of work. It's also for when you're thinking about things that you like to think about and have fun thinking about. It's just that much more fun with Smartz.

WILL: One of the things I appreciate about Smartz is getting me into the gym. It motivates me to get to the gym and also motivates me while I'm there. I don't always like being there. But if I drink a can of Smartz, I just float through the gym.

DURK: It's a real motivator. I think that if they sold the stuff at gyms, there would be a lot more renewals of memberships and people will be more likely to use the gym rather than dropping out.

WILL: What about synergy between acetylcholine and beta phenylethylamine and noradrenaline and dopamine and so forth?

DURK: Well, so far as I know, there's no direct connection between acetylcholine and beta phenylethylamine. We have been using the combination of our phenylalanine formula and our choline formula now for about 16 years. The reason for the combination is because your brain needs more than one neurotransmitter. You need more than just acetylcholine, more than just noradrenaline, and more than just dopamine. And we wanted to have something that would provide all of the above. Noradrenaline, dopamine and acetylcholine are three of the most important neurotransmitters in your brain. And Smartz helps support the production of each one.

WILL: Can you give more examples of who would profit from using Smartz?

DURK: Almost anybody who has work that requires focus, attention and concentration. For example, truck drivers make more money when they drive more hours per day. It's a very competitive field. But they've got to maintain their alertness because if they're driving down a two-lane asphalt highway in the middle of the night with a truckload of gasoline, all it takes is a momentary loss of attention and they could end up thoroughly dead. So being able to remain alert is something very valuable. I would much rather see truck drivers driving down the road in the middle of the night full of Smartz, than just plain old ordinary empty-calorie coffee.

There are also tremendous numbers of people in service positions; for example, the people who take telephone orders or take care of fouled-up orders. These people have to pay attention to what other people are saying and they need to do it all day long.


For anybody who makes a
living with their brains,
Smartz is going to
be especially useful.

SANDY: Over and over and over.

DURK: Over and over and over again. And they have to pay attention to what the person is saying or they'll make another mistake and foul up the order even further.

SANDY: And you can only get away with that when you work for the government.

DURK: That's right. You work for a private company and you're screwing up orders, or you're not fixing other people's screw ups

SANDY: You're likely to get fired.

DURK: Others who could benefit from Smartz are salespersons like real estate dealers or stock and bond brokers. I think you'll see some of the most impressive results in people who need to have a great deal of focus such as programmers who write computer code. If you let your code turn into a bowl of spaghetti, you're never going to be able to fix all the bugs in it. I really think that drinking Smartz all day long rather than high-glucose, high-caffeine colas will provide a lot more productivity. The result will be far more lines written per day with less time spent getting the darn bugs out because there will be fewer bugs to start with and because the code will be better structured.


Noradrenaline, dopamine and
acetylcholine are three of the
most important neurotransmitters
in your brain. And Smartz helps
support your brain's production
of each one.

SANDY: These conclusions are based on our own experience and on our understanding of the biochemistry that's involved.

WILL: Jack Wheeler has talked about Smartz as the "new drink for the new millennium." With the millennium bug (Y2K) and other potential disruptions down the line, there's going to be a lot of opportunity for entrepreneurial activity. And people who drink Smartz are, it seems to me, going to be able to optimize their advantages.

DURK: That's right. The future lies in the area of the intellect. One hundred years ago, a person's strength usually played a major role in their earning capability and 1,000 years ago, a person's strength was even more important.

SANDY: We still have genes that put a lot of value into physical strength. Women still are very apt to choose a man who's very strong and muscular over one who's the proverbial "90-lb weakling."

DURK: But when it comes down to the actual work of bringing home the bacon, you don't move big piles of dirt with a shovel anymore. A turbo diesel bulldozer does it with the touch of a control. The future lies with the intellect and Smartz can play a real role in helping you to use your intellect to achieve your maximum capability. Smartz can help you to be able to do it longer and more accurately and more productively. And then, at the end of the day, it can help you to feel more satisfied and to feel more rewarded about what you've done. One of the real problems with the hectic pace of modern life is working like the devil all day long. And by the end of the day you're so tired you can't sit back and think, "Yeah, I did a good job today. I feel good about that." Smartz can help prevent that tiredness and make you feel self-appreciated every day.


The future lies with the intellect
and Smartz can play a real role in
helping you to use your intellect
to achieve your maximum
capability.

If you haven't tried Smartz, do it. You may think, well gee, I usually buy soda at the supermarket and I don't really want to pay for shipping of all that water rather than the drink mix forms I've known. Well, special shipping rates have been arranged with UPS, so it's not going to be nearly as expensive as you think. And when you find out what that carbonation does for getting those nutrients into your brain across the blood-brain barrier, you are going to be amazed at what happens.

SANDY: It's really fantastic. And remember that the carbonation is not just a fun, fizzy kind of tingly flavor ingredient . . .

DURK: It is a dietary supplement/ nutrient delivery system.

SANDY: . . . it has an actual physiological function in this drink. It makes our ingredient system more readily available to your brain by helping open up the blood-brain barrier and increasing blood flow to the brain.

DURK: In fact, if it weren't for the Dietary Supplement Health and Education Act (DSHEA), the FDA would probably declare Smartz to be a medical device requiring approval.

For maximum effect, drink Smartz cold, and directly out of the can so you don't lose any CO2. Swish the Smartz back and forth in your mouth, exhaling the exsolved CO2 slowly out through your nose, thereby maximizing transport to your brain. These instructions are not FDA approved. Indeed, this entire article is not FDA approved. And the First Amendment says that we don't need their stinking approval!

(Laughter)

SANDY: Good point. If they had their way, everything would require approval.

WILL: However, if the FDA drank a lot of Smartz, perhaps the whole idea of an official approval system would be dropped. One thing is certain, right now Smartz only requires consumer approval. So go ahead, give it a try, and see if you don't approve of what getting Smartz does for you. 


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