Galantamine and Melatonin Are Brain Synergistic
One plus one equals more than two …
by Dr. Joyce Block


See this month’s article

Print this out in either format:

Open the PDF

ACROSS

3. It is widely known that sleep has an important role in memory consolidation. Furthermore, developing evidence links poor sleep to increased AD risk and memory ____. Clue: what you don't want to happen to your memory or your money

6. From the Clinical ___ in Aging study, it may be concluded that supplemental melatonin has positive effects on cognitive functioning and sleep maintenance in AD patients, suggesting a link between poor sleep and cognitive decline. Clue: acts that alter

11. What are the first names of the nutritional scientific duo whose work is reflective of the synergist process? Clue: known as the pioneers of anti-aging movement and authors of what many consider the most authoritative book on life extension

13. The results of the article’s studies also suggest that galantamine may represent a ___ inexpensive and effective therapeutic strategy in the treatment of rheumatoid arthritis. Clue: inventive

14. Neurodegeneration, such as dementia and AD, frequently produces neurobehavioral symptoms, including sleep disturbances typically characterized by ___ awakenings. Clue: opposite of daytime

DOWN

1. The researchers showed that the combined therapy of melatonin and galantamine is beneficial as it restored all the pathological ___ such as amyloid aggregates, neuroinflammation, oxidative stress, and Tau hyperphosphorylation. Clue: changes

2. Melatonin helps anticipate the daily arrival of darkness and induces ___ as well as being involved in the synchronization of circadian rhythms. Clue: “perchance to dream”

4. In a new, not-yet published study, Spanish scientists provide experimental evidence on the _____ neuroprotective effect of the combination of melatonin and galantamine. Clue: cooperative interaction

5. Melatonin is involved in harmonizing physiological functions such as sleep timing and blood ___ regulation. Clue: when people say they are stressed, they are often feeling this kind of urgency

6. In a recent study of research done at several Egyptian Universities, galantamine significantly reduced all biomarkers of ___, with the highest dose showing the best beneficial anti-inflammatory effect. Clue: a localized protective reaction to irritation, infection, or injury

7. The cholinergic activity of galantamine may repair the sleep pattern by restoring regular functions of the hypothalamopituitary axis (HPA), ___ of which is associated with cognitive disorders and insomnia. Clue: diminishment

8. Galantamine provides a dual-mode action for boosting cholinergic function, thereby boosting brain levels of acetylcholine. Thus, ___ the brain’s nicotinic receptors so as to maintain their function. Clue: regulating

9. The AChEI galantamine is an alkaloid isolated from snowdrop and ___ flowers that has been used for AD. Clue: a snow crystal

10. The Spanish study was based on an Alzheimer’s disease (AD)-related pathology model in which it was found that ______ is reduced or even absent in people with AD. Clue: a hormone released by the brain’s pineal gland

12. Melatonin has negligible ___ and is able to reduce the side effects and increase the efficacy of other drugs or nutrients. Clue: poisonous qualities

NEW CONTEST RULES BIGGER PRIZES

PRIZE
Winners receive $15 off your next order of $50 or more. First 3 correct entries win.

HOW TO SUBMIT
Send your answers in an email directly to me at:
jblock@life-enhancement.com

Simply list the answers in a numbered format (across and down)

Visit me, Dr. Joyce Block on facebook/life-enhancement with comments about your puzzle experience.

If you are a winner and want to be listed as such on our Facebook page, contact me at the link above. You are to be congratulated for the time and effort you spent in the pursuit of anti-aging knowledge.

We believe that self-education can add years to your life and life to your years.

FREE Subscription

  • You're just getting started! We have published thousands of scientific health articles. Stay updated and maintain your health.

    It's free to your e-mail inbox and you can unsubscribe at any time.
    Loading Indicator