The Durk Pearson & Sandy Shaw®
Life Extension NewsTM
Volume 19 No. 2 • February 2016


Hydrogen Gas Perfuses the Body, Promotes Better Health, By Following the Rules of Chemistry and Physics and NOW... Those of QUANTUM MECHANICS!

We have written earlier [see “Hydrogen Therapy” in the June 2012 issue of Life Enhancement] on the important protective effects of hydrogen gas, produced by fermentation by certain microbes in the gut, by scavenging the highly potent oxidant peroxynitrite as well as damaging hydroxyl radicals.

A new hypothesis proposes that hydrogen tunneling occurs in the enzymes of humans and other animals (Klinman, 2006). This phenomenal new vision points to how hydrogen changes the way enzymes such as alcohol dehydrogenase work. The idea is that “[h]ydrogen, like an electron [can tunnel] through an energy barrier...” The motions of the enzyme [in response to the movement of hydrogen] are critical for the quantum phenomenon to occur. The motions of the enzyme bring two sites, the acceptor and donor that are needed for the reaction to take place, very close together—so close that the hydrogen can move like a wave to get from one site to another.” (Mukhopadhyay, 2016).

This is amazing because, for one thing, hydrogen is 2,000 times heavier than an electron, which is known to tunnel.

The hypothesis is characterized (Mukhopadhyay, 2016): “The emerging picture is a ‘very different view of catalysis’,” says Klinman [Judith Klinman, University of California, Berkeley who, with her colleagues, did this work]. “The role of the whole protein, through these fluctuating conformations, is to bring things so close that quantum mechanics starts to take over, even at room temperature.”

This very new field of science, quantum biology, is sure to open up many new ways of looking at disease. In the case of hydrogen, as much as we now know of its beneficial effects on biological mechanisms, we can look forward to much more that it can do beyond that via the, perhaps, surprising field of quantum mechanics.

What this means is that hydrogen may be doing a great deal more in the body when hydrogen is generated by certain bacteria in the gastrointestinal tract than has been previously understood—for example, scavenging hydroxyl radicals and peroxynitrite. Incidentally, peroxynitrite, a powerful oxidant, has been identified as a key factor in the development of heart failure (Carnicer, 2013), of fibrosis (Daiber, 2013), and in others.

It is interesting to note that hydrogen is, by far, the fastest moving molecule in one’s body, even without the additional boost of enzymatic motions.


  • Klinman. Linking protein structure and dynamics to catalysis: the role of hydrogen tunneling. Philos Trans R Soc Lond B Biol Sci. 361(1472):1323-31 (2006).
  • Mukhopadhyay. Quantum Biology. ASBMB Today. (January 2016).
  • Carnicer, et al. Nitric oxide synthases in heart failure. Antioxid Redox Signal. 18(9):1078-99 (2013).
  • Daiber et al. Protein tyrosine nitration and thiol oxidation by peroxynitrite—strategies to prevent these oxidative modifications. Int J Mol Sci. 14:7542-70 (2013).

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