Hesperidin Combats Aluminum-Brain Disorders
Stop Frying Your Brain
by Dr. Joyce Block

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2. Hesperidin has been added to Pearson & Shaw’s product called _____. Clue: Galantamine formulation, first of two words in the name.

4. Being sensitive to stimuli originating from outside of your body is known as being _____. Clue: Look to the right of the frying pan image in the article for the answer.

5. ___ may be good candidates for therapeutic implications of AD due to their ubiquitous nature and fewer side effects along with long lasting benefits. Clue: Biologically active compounds found in plants.

7. AI has been reported to cause oxidative stress associated with apoptotic neuronal ___ in the brain. Clue: What you don’t want at the end of your financial report.

8. Although long suspected, ___ has only recently been found to be a major risk factor for the cause and development of Alzheimer’s disease (AD). Clue: A light silvery-grey metal commonly used in everyday products. (Check out which ones. Read labels).

11. Aluminum enters into the brain via diet, ___, cosmetics, toothpastes, inhaled fumes/particles, cooking utensils, and even through drinking water. Clue: The “cure” for stomach acid (pl.). Is the cure worse than the disease?

12. Hesperidin, a phytoflavanone that exists abundantly in citrus fruits, is reported to___ the blood–brain barrier easily due to its lipophilic nature. Clue: Go to the other side.

14. . . . “Hesperidin, a flavonoid found plentifully in citrus fruits, can help protect your brain from the ravages of aging and, based on newer discoveries about it, may help reduce the risk of Alzheimer’s disease. . . .” Clue: Who said this? Clue to clue: They are two anti-aging scientists. First names only.


1. Albert ___was said to love lemons, a high hesperidin citrus fruit. Clue: A name people use to describe a really smart person.

3. ____ is a bioflavonoid found in citrus fruits such as limes, lemons, oranges, and grapefruit. Clue: Easy answer—the subject of this article.

6. The Indian researchers investigated the protective effect of hesperidin against aluminum chloride (AlCl3)-induced cognitive impairment, oxidative stress and ___. Clue: A genetically directed process of cell self-destruction.

9. ___loss can be caused by aluminum intoxication (AI). Clue: The faculty by which the mind stores and remembers information.

10. The process by which hesperidin reversed AI was through lessening acetylcholine esterase activity and the expression of amyloid β biosynthesis related ____. Clue: Thing serving as a standard of comparison or as an indication of what may be expected.

13. The main researchers named in this article can be found at a university in ____. Clue: Saffron is one of this country’s most delicate and pricey spices. Yum.


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