The Durk Pearson & Sandy Shaw®
Life Extension NewsTM
Volume 19 No. 3 • April 2016


FAST FACTS:

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“TOR [a growth promoting gene activated by food] inhibition [ ] stimulates AUTOPHAGY [cellular self-digestion], which, as in insulin/IGF-1 mutants, is REQUIRED FOR LIFE EXTENSION (at least in worms and flies).” (emphasis added) (That is, AUTOPHAGY is required for life extension in worms and flies. It may be required in other organisms.) (Cynthia Kenyon, Nature. Mar. 2010)

Autophagy is induced by limiting caloric intake, promoting the cellular self-digestion to obtain energy and raw materials in the absence of adequate amounts of food. However, some natural substances can also induce autophagy, including TREHALOSE, an osmolyte found in our FOLDRIGHT.

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