EDITORIAL

How to Increase Your Lifespan …
By Increasing Your Healthspan


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T he graph on page 2 first appeared over 30 years ago. It was a view based on what life extension scientists then thought to be a plausible future. The principal idea was that with advances in health it would not only be possible for individuals to live longer increasing lifespan, it would also be possible to increase healthspan so that the slings and arrows of a lifetime would take a more gradual toll.


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Here’s another curve, albeit an even more hopeful one: Just now, healthy individuals are rising up this curve—where a great many or us are now nearing the yellow dot—where the amount and quality of life is increasing for every added year.

The idea, which seems feasible based on demographic evidence, is that every year lifespan increases, as if there is no end in sight. And if there were a limit to lifespan, the velocity of increase would be slowing … but it is not. Longevity escape velocity is a term used in life enhancement and life extension. It is a point in time for an individual when life expectancy is being extended longer than the time that is passing.

Leading Causes of Death… and what can be done about each death threat NOW!


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Data published by the Center for Disease Control ostensibly provide the information for this graphic list, except for Alzheimer’s disease and septic shock. The Alzheimer’s position (now # 3) is supported by an article in a recent issue of Neurology finding that the death certificates of those with Alzheimer’s usually lists consequences of the disease rather than Alzheimer’s disease. For example, pneumonia was recorded on President Reagan’s death certificate, rather than Alzheimer’s. Because of this tendency, the actual number of Alzheimer’s deaths is actually 6 times higher (503,000, rather than 83,000), moving it significantly higher on the cause of death rankings.

Also based on CDC data, the number of times people were in the hospital with sepsis increased from 621,000 in the year 2000 to 1,141,000 in 2008. And of those who get sepsis, between 28 and 50 percent die of septic shock. That’s between about 320,000 to 570,000 deaths per year. Thus, it now appears in position # 4.

Heart Disease

Of all the beneficial nutritional supplements you can take, Omega-3 Fish Oil is at the top of the list. It represents the biggest bang for your buck. Regular use can reduce your risk from sudden death heart attack by 50–80%. Sudden death heart attack is the single largest cause of death in the U.S., coming in at 325,000 adult deaths each year. All you need do is take 2–3 g of Omega-3s (as DHA and EPA) per day. Make sure the supplements you take are double distilled with added antioxidant protection (vitamin E, fat-soluble C, and diosmin).

Omega-3s also reduces death from arrhythmias, including ventricular fibrillation (the most commonly identified arrhythmia in cardiac arrest) and tachycardia (when heart rate exceeds normalcy). Omega-3s also diminish thrombosis (formation of blood clots), and thus helps prevent myocardial infarction (heart attacks)

Omega-3s can also inhibit the development of atherosclerosis, Surprisingly, the average intake among Americans through the food supply is minuscule. And by the way, the body cannot make DHA or EPA, so supplementing is crucial.

Also, way up on the list of preventative supplements is CoEnzymeQ10. This oil-soluble, vitamin-like substance is present in most cells, primarily in the mitochondria. It is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. Ninety-five percent of the human body’s energy is generated this way. CoQ10 improves chronic heart failure symptoms and reducing major cardiovascular events. One study showed a 44% reduction of mortality. You should also know that statins inhibit the production of CoQ10.

Then there is natural thyroid hormone. Analyses of studies show that even subclinical hypothyroidism poses substantial risk for coronary artery disease. Taking a thyroid supplement can reduce this vulnerability.

Still focusing on Heart Disease, a good bet is to add pomegranate juice to your diet. As little as 8 oz per day of sugar-reduced pomegranate juice can improve myocardial perfusion in those with coronary heart disease. Pomegranate juice can also inhibit an enzyme that causes vasoconstriction. It also reduces systolic blood pressure, while it raises the activity of HDL, the good cholesterol, and protects it.

Not to be missed also is vitamin B3, aka Niacin, This B vitamin can reduce total cholesterol, reduce LDL (the bad cholesterol by 25%, triglycerides by 50%, and at the same time increase HDL, the good cholesterol.

Dr. Ward Dean, the renowned bio-gerontologist has remarked that Niacin has been shown to reduce non-fatal heart attacks by 26% in just 6 years. At the same time, it reduced strokes by 24%, and reduced mortality, adding two more years of life.

It is startling to know that nearly 50% of all heart attacks occur in people with “normal” cholesterol levels. Inflammatory conditions may be to blame and therefore you should add several tests to your usual blood work. In addition to Oxidized LDL, among the new tests are MPO, indicative of inflammatory changes on your blood vessels and F2-isoprostanes, a urine test for telling you if your fat cells are participating in inflammatory changes.

Higher intakes of Omega-3s have favorable effects on other factors related to cardiovascular risk, including blood pressure and heart rate. As well, Potassium Bicarbonate has been shown to be quite beneficial. Even the FDA says, “Potassium is beneficial in lowering blood pressure.”

Cancer

# 2 in terms of what you’re likely to die from is cancer, so it’s important to take whatever reasonable steps you can. Selenium has anti-carcinogenic effects, which is a major reason why this mineral is supplemented by so many people. The selenite form appears to be more effective than other forms. A recent review reported significantly reduced incidences of lung, colon, and prostate cancers by 46%, 58%, and 64%, respectively.

Vitamin D3 is another inexpensive nutritional supplement that helps reduce the risk of most cancers. Cancer patients with high levels of vitamin D3 (at the point of diagnosis) often have better survival rates and remain in remission longer than patients who are vitamin D3-deficient.

Alzheimer’s Disease

In the # 3 position of what you’re likely to die from is Alzheimer’s disease. Galantamine is an important nutrient that helps prevent the abnormal breakdown of acetylcholine, an important memory molecule that is necessary for proper memory function, particularly focus and concentration

Galantamine also helps your nicotinic receptors to work properly. This receptor has long been know to influence memory function. Galantamine is the same memory-function enhancer used 3200 years ago by the Greek hero Odysseus, the champion of memory and the enemy of forgetfulness.

New neurons, essential brain cells, are good to have and galantamine can enhance them by improving memory, spatial navigation, and pattern separation in the hippocampus, the part of your brain where information is consolidated.

Choline, an important nutrient, is the precursor of acetylcholine, an important neurotransmitter that is necessary for proper cognitive and memory function. Loss of cholinergic neurons is associated with Alzheimer’s disease.

Choline is needed for adequate growth hormone release. Choline reduces homocysteine, high levels of which are associated with Alzheimer’s.

Turmeric is an important brain antiinflammatory, high levels of which are associated with low levels of Alzheimer’s. It contains its own system of antioxidants, each operating together as a system. Indian Jainists ceremoniously pour turmeric over the head of one of their deities. In certain parts of India where turmeric use in curries is highest, Alzheimer’s disease is extremely low.

Turmeric improves working memory. One of its many active ingredients, turmerone induces neural stem cell proliferation. This is good for proper memory function.

Lithium: in one study, it sharply reduced the production of amyloid-beta, an established cause of Alzheimer’s disease. It also increases grey matter, the loss of which is associated with Alzheimer’s disease.

EGCG from Green Tea Polyphenols may help prevent or reduce the progression of Alzheimer’s. EGCG and Omega-3s act synergistically to inhibit cerebral amyloid-beta deposits.

Not only good for cancer, when Vitamin D3 levels are low, there is a 53% increased risk of developing dementia, and when there is severe deficiency, there is a 125 % risk.

When Vitamin D3 levels are low, there is a 69% increased risk of developing Alzheimer’s, and when there is severe deficiency, the risk reaches 122%. High levels of vitamin D3 decrease dementia

Vitamin D3 can increase your healthspan and your lifespan. Vitamin D3 deficiency predicts cognitive decline in older men and women. A combination of calcium plus Vitamin D3 resulted in a 49% reduction in falls as compared to calcium alone. Falls are a major cause of death.

Septic Shock

In the # 4 position is septic shock, a severe medical condition that results from sepsis, the presence in tissues of harmful bacteria and their toxins, typically caused through infection of a wound. Septic shock causes multiple organ failure (MOF), which can simultaneously destroy many of the body’s organs, resulting in death. In that regard, it is similar to Ebola.

The CDC figures show 1,141,000 cases of sepsis in 2008! The mortality rate from septic shock is as high as 50%, taking up to 570,000 lives. DXM (dextromethorphan), an inexpensive OTC cough medicine has been shown to be effective in rats and mice for the treatment of sepsis.

Arginine is an amino acid that promotes wound healing, and thus may reduce vulnerability to sepsis. Arginine has an essential role in infection and sepsis. Deficiencies in arginine (and citrulline) may underlie the detrimental outcome of inflammatory conditions, such as sepsis and septic shock.

Thoughtspan

In addition to all of the ways that you can increase your lifespan and your healthspan, consider thoughtspan. This can be done by enhancing your ability to improve your memory and cognitive functions through the use of select supplements.

Become a Life Extension Methuselah

Recent research points to a pile-up Transthyretin as the cause of death in supercentenarians. This results from protein misfoldings that build up in blood vessels. Osmolytes such as trehalose and creatine can help prevent this.

Would You Like To Enjoy Life More?

Would you like to feel a greater reward in life for everything that you accomplish? EGCG, Taurine, Quercetin, Hesperidin, and Lithium can help!

Coming Soon

Just around the corner, our smartphones will enable us to access a plethora of health information inside our bodies. Information about our blood, our chemistry, our DNA, our physiological state, and much, much will be instantly available.

This arrival is coming faster than you think, and will represent a huge health enhancement.

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