Unique Protection Against
Gingivitis and Dental Plaque

Now you can expand upon the principles of good dental hygiene by adding a potent antibacterial, antiplaque mouthwash to your oral care program: the world's first mastic mouthwash. It uses the same antibacterial phytonutrient found in a breath-freshening mastic toothpaste. It is not only a companion to the toothpaste but also a collaborator in the fight against bacteria, doing battle against P. gingivalis, the principal cause of bad breath, gingivitis, and periodontal disease. It also combats bacteria such as S. aureus, S. pyogenes, C. albicans, S. mutans, and on up to the fearsome H. pylori, the cause of ulcers.

Mastic mouthwash is a great-tasting, refreshing, and convenient way to show those germs that you mean business and that you will not be distanced - "even your best friends won't tell you" - from loved ones, your friends, and your teeth (gingivitis leads to periodontal disease, which leads to loss of teeth).

Plaque, the Villain
The chief villain in our mouth is tooth plaque, formed mainly from microbes that accumulate on the surface of our teeth. These microbes transform sugar-producing acids, which are hospitable to the creation of plaque. In one study, when the dental plaque obtained from 380 periodontally healthy adults and 139 periodontitis patients was analyzed, P. gingivalis was detected in 36.8% of the healthy subjects and in 87.1% of the periodontitis patients.1

Tooth plaque can cause gingivitis, an inflammatory tissue reaction and the predominant form of periodontal disease in adults. Mastic oil helps to harness the activity of the blood's first-line-of-defense protection, the leukocytes (white blood cells) and multinucleocytes, thereby increasing tissue defense, especially between the teeth and gums, where gingivitis and plaque occur.

In a study at Aristotle University in Greece, mastic was found to reduce bacterial plaque by 42% when allowed to contact the gum tissue.2 Twelve students from the university abstained from all means of dental hygiene for ten days, after which they bathed their mouths with mastic three times daily for five days. On the fifth day, the amount of plaque was determined, and pictures were taken. What was shown was a clear reduction in dental plaque from the ten-day accumulation.

Leukocytes, and especially the multinucleocytes, as elements of the blood, exist physiologically in the liquid found in the gingiva (the crevices between the teeth and gums). When mastic is applied to these areas, an active agent in it attracts the defending leukocytes and multinucleocytes to the area of irritation.

Mastic was thus found to reduce harmful properties (toxins) in the bacterial plaque (white-cell infiltration) from the liquid found in the gingiva. With systematic use of mastic, the amount of bacterial plaque was reduced by 41.5% in comparison with the ten-day period when the students weren't using any oral health product.
The Design of Mastic Mouthwash
Mouthwashes are mixtures of many ingredients. A good one is likely to use a variety of agents, such as glycerine for body and flavor; anticaries agents, such as fluoride; tartar-control ingredients, such as a natural phenolic-rich menthol; an antioxidant and antibacterial such as mastic oil; pH buffers; humectants (agents that prevent dry-out, increase saliva, and improve what is known as mouth-feel); and whiteners, such as aqua. The mastic mouthwash is designed in accordance with the latest research, emphasizing the use of natural ingredients.

In addition to mastic oil, it contains glycerine, sorbitol, castor oil, and menthol, among other good ingredients.

Introducing mastic oil and extracts of mastic gum into mouthwash and toothpaste helps to reduce plaque and gum diseases while enabling these products to serve as antiseptics and mouth deodorants.

Mastic in Every Mouthwash
French biochemist René-Maurice Gatefosse mentioned in his work that mastic has been used directly on tooth decay with positive results by dentists.3 He believed that there is strong evidence showing that mastic serves as an oral antiseptic and that it preserves and strengthens gums and teeth. He also declared that mastic could be used in dentistry as a material for fillings and that all toothpastes should contain mastic oil as their main active ingredient. The same holds true for mouthwash.

Anticaries, Antibacterial Additions
Dental caries is a disease that progresses when bacteria produce an acid (as a byproduct of carbohydrate fermentation) that diffuses into the teeth and dissolves their mineral components, causing demineralization.4 Together with periodontal disease, dental caries comprises the bulk of major oral disease. Pathological factors such as disease-causing bacteria, salivary dysfunction, and dietary carbohydrates are related to caries progression. But unlike the ability of periodontal bacteria to be sufficient for disease, caries bacteria require an accomplice: carbohydrates. In ancient times, caries depended to a significant degree on the diet, but until the rise of processed carbohydrates, these compounds did not represent a significant contribution to tooth loss - unlike periodontitis.5 Fermentable carbohydrates, including sugars, are generally accepted to be the fundamental cause of caries.

The Fluoride Controversy
There has been much negative press about fluoride, especially its addition to municipal water supplies by local and regional governments. However, studies have shown that limited use of fluoride in toothpaste or mouthwash is not a problem, and in appropriate amounts is beneficial. Certain individuals, especially children, can get too much fluoride, which can cause dental fluorosis, a discoloring of the teeth. Thus children should be supervised when using fluoridated toothpaste, lest they eat it and become susceptible.7 However, the amounts required are fairly large, so fluorosis is not very common.

Allegations concerning other problems (remember General Jack D. Ripper, the war-crazed loony in Stanley Kubrick's Dr. Strangelove?) are unfounded. Advocates of fluoride in toothpaste span the natural spectrum from Dr. Andrew Weil to Tom's of Maine.

Dental cavities (caries) are preventable. In 1802, Italian dentists noticed that patients who came from areas rich in fluoride had far less caries. Word spread, and dentists in Europe recommended to their patients that they suck on lozenges containing fluoride mixed with honey. Today, much of our water supply is fluoridated, although the value is probably insignificant, given the widespread use of fluoride in toothpaste and mouthwash. Indeed, reviews of the literature indicate that ingested fluoride (as in the water supply) does not have the same effectiveness as topical fluoride (as in toothpaste).6

Fluoride acts on both the local and systemic levels. Locally, it prevents the surface demineralization of enamel by inhibiting bacterial activity and strengthening the superficial layers. Systemically, it improves the resistance of the enamel by forming a strong, calcium-bonded coating.

Mastic Mouthwash is More
Just about everything in the mastic mouthwash is state-of-the-art for an efficient means to ward off the kinds of bacteria that have made the history of dentistry so excruciating. And as we now know, these bacteria are strongly suspected of playing a role in fomenting other degenerative diseases as well (see Discovering Antibacterial Mastic - Apr. 1999). Moreover, mastic mouthwash can help increase the quality of nature's bacteria-fighting enzymes in your saliva and marshal your body's defense system, while it brightens your smile and sweetens your breath.


  1. Amano A, Kuboniwa M, Nakagawa I, Akiyama S, Morisaki I, Hamada S. Prevalence of specific genotypes of Porphyromonas gingivalis fimA and periodontal health status. J Dent Res 2000 Sep;79(9):1664-8.
  2. Topitsoglou-Themeli V, Dagalis P, Lambrou D. A Chios mastiche chewing gum and oral hygiene. I. The possibility of reducing or preventing microbial plaque formation. Hell Stomatol Chron 1984 Jul-Sep;28(3):166-70.
  3. Perikos J. The Chios Gum Mastic. Print All Ltd: Athens, 1993.
  4. Featherstone JD. Prevention and reversal of dental caries: role of low level fluoride. Community Dent Oral Epidemiol 1999 Feb;27(1):31-40.
  5. Linossier A, Gajardo M, Olavarria J. Paleomicrobiological study in dental calculus: Streptococcus mutans. Scanning Microsc 1996;10(4):1005-13; discussion 1014.
  6. Limeback H. A re-examination of the pre-eruptive and post-eruptive mechanism of the anti-caries effects of fluoride: is there any anti-caries benefit from swallowing fluoride? Community Dent Oral Epidemiol 1999 Feb;27(1):62-71.
  7. Triller M. Fluoride, a preventive agent of caries: mechanisms, sources, risks. Arch Pediatr 1998 Oct;5(10):1149-52.

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