Review of The Omega-3 Connection by Andrew L. Stoll, M.D.
Simon & Schuster, New York, 2001. Hardcover, 340 pages.
Save Your Life With Omega-3 Oils

Now you can restore your body's natural balance and treat depression, reads the jacket blurb on Dr. Andrew Stoll's new book, The Omega-3 Connection. What an understatement that is!

Dr. Stoll believes that more than 70,000 lives could be saved each year in the United States alone if Americans had sufficient omega-3 oils in their bodies. He marshals the evidence that omega-3 oils (which are most commonly found in cold-water fish) are a positive juggernaut for supporting cardiovascular health (see Omega-3 Fish Oils Promote Cardiovascular Health - Jun. 1999). Not only do they help prevent arterial plaque formation and blood clotting, but they also help to guard against cardiac arrhythmias and reduce the incidence of ischemia (insufficient blood flow to the tissues).

Moreover, there is evidence that omega-3 fish oils can directly benefit certain muscle cells of the heart, protect the kidneys, alleviate rheumatoid arthritis, abate inflammatory bowel diseases, reduce episodes of transplant rejection, provide protection from infection, and even sharpen cognitive function. All of this is skillfully presented in Dr. Stoll's fine book.

Dr. Stoll is not given to hyperbole. On the contrary, this Harvard Medical School doctor is thoughtful, methodical, philosophically wise, and insightful. As well, he is the author of a pace-setting study that we reported on in Omega-3 Fish Oil for Mood Swings - Jul. 1999. There we said: "Now, in a dramatic expansion of its already known abilities to influence desirable membrane characteristics in the brain, omega-3 fish oil has been found to ameliorate a certain type of depression that may be more common than you think. A type of depression characterized by wide and often frightening mood swings - bipolar disorder, also known as manic-depressive illness - has been found to be significantly improved by intake of omega-3 fatty acids, which are commonly derived from fish oil.1

"In a double-blind, placebo-controlled study published in the May issue of the Archives for General Psychiatry, 30 patients suffering from bipolar disorder were given two omega-3 fatty acids - eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) - as supplements for a 4-month period. This regimen produced significant reductions in depressive symptoms in the experimental group. According to the lead author, Dr. Andrew Stoll of Harvard Medical School, 'This study may represent the first demonstration of an effective therapy for bipolar disorder.'"2

Make no mistake, The Omega-3 Connection could be one of the most important books you'll ever read on health, because if you implement its ideas, you will improve the quality of your life and may very well lengthen it.


  1. Stoll AL, Severus WE, Freeman MP, Rueter S, Zboyan HA, Diamond E, Cress KK, Marangell LB. Omega 3 fatty acids in bipolar disorder: a preliminary double-blind, placebo-controlled trial. Arch Gen Psychiatry 1999 May;56(5):407-12.
  2. Stoll A et al. Comment in Arch Gen Psychiatry 1999 May;56(5):413-16.

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